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Calcium Fructoborate Nanoparticles: Plant-Based Carrier Boron as Potential Medicine for Neutron Cancer Therapy

Credit to Download: 1 | Page Numbers 13 | Abstract Views: 45
Year: 2018
COI code: ICESIT01_091
Paper Language: English

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Authors Calcium Fructoborate Nanoparticles: Plant-Based Carrier Boron as Potential Medicine for Neutron Cancer Therapy

  Faeqeh Pirouz - Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
  Ghasem Najafpour - Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
  Mohsen Jahanshahi - Faculty of Chemical Engineering, Babol Noshirvani University of Technology, Babol, Iran
Mazyar Sharifzadeh Baei - Department of Chemical Engineering, Islamic Azad University, Amol, Iran

Abstract:

Boron neutron capture therapy (BNCT) is efficient therapeutic methods in cancer treatment based on nuclear capture and fission reactions. In this method, use of the best boron-containing agents for boron therapy and boron delivery agent for delivery of them to the infectious site are key points in therapy efficiency. Our research indicated that calcium fructoborate was the best compound as a boron-containing agent for boron therapy. Furthermore, studies have demonstrated that liposomes can effectively and selectively deliver large quantities of boron to tumors and that the compounds delivered by liposomes have a longer tumor retention time. Indeed, liposomal encapsulation of calcium fructoborate has been extensively evaluated as nanovehicles for the delivery of boron compounds for BNCT.In this paper, we deeply investigate molecular composition of the calcium fructoborate used as a carrier supplement for cancer therapy, by using FT-IR, XRD, TG, DSCand Raman spectroscopic analysis. The experimental measurements agree very wellwith the molecular formula Ca[(C6H10O6)2B]24H2O

Keywords:

Boron neutron capture therapy, calcium fructoborate, liposome encapsulation

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COI code: ICESIT01_091

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Pirouz, Faeqeh; Ghasem Najafpour; Mohsen Jahanshahi & Mazyar Sharifzadeh Baei, 2018, Calcium Fructoborate Nanoparticles: Plant-Based Carrier Boron as Potential Medicine for Neutron Cancer Therapy, The first international congress and international exhibition of science and technology, بابل, دانشگاه صنعتي نوشيرواني بابل, https://www.civilica.com/Paper-ICESIT01-ICESIT01_091.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Pirouz, Faeqeh; Ghasem Najafpour; Mohsen Jahanshahi & Mazyar Sharifzadeh Baei, 2018)
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Type: state university
Paper No.: 5220
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