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Effects of low-dose contraceptive pills on the risk factors of cardiovascular diseases among 15-35-year-old women: A retrospective cohort

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Year: 2019
COI code: JR_IJRM-17-11_007
Paper Language: English

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Authors Effects of low-dose contraceptive pills on the risk factors of cardiovascular diseases among 15-35-year-old women: A retrospective cohort

  zhran momeni - Deputy of Health, Bushehr University of Medical Sciences, Bushehr, Iran.Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University ofMedical Sciences and Health Services, Yazd, Iran.
  ali dehghani - Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
  hossein Fallahzadeh - Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
  Moslem Koohgardi - Department of Health Education and Health Promotion, Faculty of Health, Rafsanjan University of Medical Sciences and Health Services, Kerman, Iran.
  Maryam Dafei - Department of Midwifery, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
  Masoud Mohammadi - Department of Nursing, Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Abstract:

Background: Cardiovascular diseases could be preventable; as a result, understanding the risk factors was regarded as the major priority for healthcare providers. Objective: The main objective of this research was to achieve a deeper insight into the effect of long-term use of low-dose oral contraceptive pills (OCP) on the risk factors of cardiovascular diseases. Materials and Methods: This research was a retrospective cohort conducted (historical and prospectively) conducted on 100 women with normal menstrual cycles aged 15 to 35 yr, who were referred to the healthcare centers in Yazd, Iran. The participants were categorized into two groups: The OCP group was consuming the pills for 0-3, 4-23, and 24-36 months, and the non-OCP group. Participants were followed up for a minimum of 3 months and a maximum of six months.Results: The highest level of low-density lipoprotein (LDL), homocysteine, cholesterol, triglyceride levels, and systolic blood pressure was observed in the OCP group in the duration of 24 to 36 months. The Tukey’s test demonstrated that there were comprehensible differences in the LDL (p = 0.01), cholesterol (p = 0.01), triglyceride (p < 0.001), and homocysteine levels (p < 0.001), also systolic blood pressure (p = 0.04). Conclusion: It was realized that the long-term consumption of low-dose OCP can augment the incidence of some risk factors (systolic blood pressure, homocysteine levels, cholesterol, LDL-c, and triglyceride) and lead to developing cardiovascular diseases amongst the healthy women.

Keywords:

Birth control pills, Homocysteine, Nitric oxide, Dyslipidemias, Coronary artery diseases.

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COI code: JR_IJRM-17-11_007

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momeni, zhran; ali dehghani; hossein Fallahzadeh; Moslem Koohgardi; Maryam Dafei & Masoud Mohammadi, 2019, Effects of low-dose contraceptive pills on the risk factors of cardiovascular diseases among 15-35-year-old women: A retrospective cohort, International Journal of Reproductive BioMedicine 17 (11), https://www.civilica.com/Paper-JR_IJRM-JR_IJRM-17-11_007.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (momeni, zhran; ali dehghani; hossein Fallahzadeh; Moslem Koohgardi; Maryam Dafei & Masoud Mohammadi, 2019)
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Type: Medical University
Paper No.: 426
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