A review on secondary metabolites and pharmacological effects of Berberis sp

Berberis sp. is a medicinal plant, native to northeastern Iran and used in traditional medicine for many disorders. Several studies have been conducted to detect its herbal components and therapeutic characteristics. This review article has introduced herbal components and assessed its valuable therapeutic properties. The information in this review article has been gathered from journals accessible in databases such as SID, MagIran, and Civilica. The search terms were Berberis and antioxidant activity. Several drug properties, such as antimicrobial, antifungal and anti-parasitic properties, are related to phenolic compounds of barberry. The most antioxidant activity of Berberis sp. extracts is due to alkaloids with an isoquinoline core such as Berberine, Oxyaconthine oxide, Berbamine, and Palmatine. Berberis sp. has therapeutic effects such as low blood cholesterol, high blood pressure, anti-inflammatory effects and antioxidant properties. Traditional applications of Berberis sp. in the treatment of many diseases and its valuable medicinal and herbal components could provide a context for scientists to develop plant-derived medications such as antibiotics, high cholesterol-lowering drugs, blood pressure treating drugs & joint pain medication and the key to conducting clinical trials.

Keywords:

Berberis sp. , Compounds , Pharmacological effect , Traditional medicine