Effect of L-Carnitine on memory retention on passive avoidance learning in normal and ovariectomized adult female rats
Publish Year: 1393
نوع سند: مقاله کنفرانسی
زبان: English
View: 848
This Paper With 13 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
BSCONF01_620
تاریخ نمایه سازی: 15 بهمن 1393
Abstract:
Background: L-carnitine is of considerable interest because of its capacity to counteract several physiological and pathological phenomena typical of brain aging processes.Materials and method: The present study investigated the effect of L- carnitine on memory retention of passive avoidance learning in normal and ovariectomized rats. We examined the effects of L-carnitine on the learning ability of normal and ovariectomized rats. L-carnitine (1, 5 and 10 mg/kg b.w.) was administered orally to normal and ovariectomized adult female Wistar rats for a period of 30 days. Results:Our results showed that oral administration of L-carnitine increased step-through latency time and decreased time in dark compartment in passive avoidance tasks in rats. Conclusion: It is concluded that L-carnitine increased memory retention in rats. It is suggested that L-carnitine must be considered as an alternative/adjunctive treatment to potentiate memory retention.
Keywords:
Authors
Nasrin abolhasan pour
PhD Student of Physiology, Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran