Studying the relation of blood lead level with the thyroid hor mones and blood factors

Background and Purpose: Lead has many applications in the industry but does not play a spe cific physiological role in the body. According to performed studies, lead has an undesirable ef fect on the nervous, gastrointestinal, respiratory, and endocrine systems. People who are highl y exposed to this element, due to their occupation or living place, are affected by its harmful ef fects. The aim of this study was to evaluate the level of thyroid hormones and blood cells in pe ople highly exposed to lead.Analysis method: This cross-sectional study was carried out on 37 patients with high exposur e level lead in Tehran. After filling out the consent form and questionnaire, the blood samples were collected from them and their levels of blood lead, thyroid hormones and blood paramete rs were evaluated in a laboratory. Normal distribution of data was assessed by Kolmogorov S mirnov test by Med Calc 14.8.1.Results: There was no significant association between blood lead levels and levels of thyroid hormones, number of blood cells and related blood cells parameters (HCT, HGB, MCV, MCH and MCHC); however, ther was a weak link between blood lead levels and age (r = 0.25).Conclusion: High lead levels did not effect on the level of the thyroid hormones, the number o f blood cells and the levels of the red blood cells parameters.

Keywords:

Lead , Thyroid hormones , Blood cells , Hemoglobin , Hematocrit