Magnetic nanoparticles and their application in drug delivery

The blood–brain barrier (BBB) represents an insurmountable obstacle for a large number of drugs,including antibiotics, antineoplastic agents, and a variety of central nervous system (CNS)-active drugs,especially neuropeptides. One of the possibilities to overcome this barrier is a drug delivery to the brainusing nanoparticles. The application of nanotechnology for cancer therapy has received considerableattention in recent years. Cancer nanotechnology (an interdisciplinary area of research in science,engineering and medicine) is an upcoming field with extensive applications. Among the broad spectrum ofNano scale materials being investigated for biomedical use, magnetic nanoparticles (MNPs) have gainedsignificant attention due to their intrinsic magnetic properties, which enable tracking through the radiologycornerstone, magnetic resonance (MR) imaging. This class of NPs includes metallic, bimetallic iron oxidesuper paramagnetic iron oxide nanoparticles (SPIONs). In this review Article, the intrinsic properties ofmagnetic NPs were exploiting to obtain medical breakthroughs in diagnosis, and drug delivery. Perhapsthe most promising applications relate to the diagnosis and treatment of cancer. It provides a uniqueapproach and comprehensive technology against cancer through early diagnosis, prediction, prevention,personalized therapy and medicine. Target-specific drug therapy and methods for early diagnosis ofpathologies are the priority research areas in which nanotechnology would play a vital part.

Keywords:

Nanoparticle , Drug Delivery , Magnetic , Nano composite