Published in: 12th Congress of Iranian Genetics Society
COI code: CIGS12_0325
Paper Language: English
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Authors Association of the insulin-like growth factor-I (IGF-I) gene polymorphism with milk production traits in Iranian HolsteinZ Karimi Kurdistani - Department of Animal sciences, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran
J Rostamzadeh - Department of Animal sciences, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran
M Nazari - Department of Animal Sciences, The Ohio State University, Columbus, USA
O Azizi - Department of Animal sciences, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran
Abstract:PCR-SSCP analysis of the 5' flanking region of the bovine insulin-like growth factor-I (IGF-I) gene was used to screen polymorphisms in a total of 287 cattle belonging to three populations: Holstein (H), Kurdish (K) and crossbred (1/2 H × 1/2 K) reared in the west of Iran. IGF-I amplified fragments from homozygous individuals were sequenced and aligned. Sequencing showed a C/T transition at position -472 according to the GenBank sequence AF210383. The observed heterozygosity, as well as Ne and polymorphism information content (PIC) values in the IGF-I gene, indicate high genetic variability in the Holstein breed. General linear mixed effect models (GLMMs) revealed that the presence of allele A in IGF-I was associated with increased MY and the presence of allele B was associated with decreased 305-day protein yield (PY) and 305-day fat yield (FY) (P < 0.1). Animals that possessed the AA genotype were favorable for MY (P < 0.05), PY and FY (P < 0.1). These results suggest that variation in the bovine IGF-I gene is associated with milk production traits in Iranian Holstein cattle
Keywords:cattle, gene polymorphism, IGF-I, milk traits
COI code: CIGS12_0325
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Karimi Kurdistani, Z; J Rostamzadeh; M Nazari & O Azizi, 2012, Association of the insulin-like growth factor-I (IGF-I) gene polymorphism with milk production traits in Iranian Holstein, 12th Congress of Iranian Genetics Society, تهران, انجمن ژنتيك ايران, https://www.civilica.com/Paper-CIGS12-CIGS12_0325.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Karimi Kurdistani, Z; J Rostamzadeh; M Nazari & O Azizi, 2012)
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Type: state university
Paper No.: 4340
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