New Concepts in Recombinant Human Interefronβ

The production of human proteins for diagnostic and therapeutic applications is a still increasing field of research, and the first true industrial use of recombinant DNA technology. Escherichia coli as the best characterised and most widely used bacterial host can be combined with a lot of different vectors and expression systems. Most proteins applied in therapy and diagnosis (e.g., hormones, growth factors, or recombinant antibodies) are secreted proteins. Interferon-beta (IFN-β) ismessenger molecule, whose formation is increased in infections and cancer diseases. Consequently, it is often administeredtherapeutically. Amongst other things, it prevents formation of new blood vessels within a tumour, thus inhibiting its growth

Keywords:

Interferon beta , Recombinant protein , Cancer immunology