CIVILICA We Respect the Science
Publisher of Iranian Journals and Conference Proceedings
Paper
title

An Evaluation on Regulatory Role of Micro RNAs on NKX2-1: A Responsible Gene in Lung Cancer

Credit to Download: 0 | Page Numbers 1 | Abstract Views: 57
Year: 2018
COI code: CIGS15_163
Paper Language: English

How to Download This Paper

For Downloading the Fulltext of CIVILICA papers please visit the orginal Persian Section of website.

Authors An Evaluation on Regulatory Role of Micro RNAs on NKX2-1: A Responsible Gene in Lung Cancer

  Mohammad Mokhtari - Department of biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran
  Seyed-Morteza Javadirad - Department of biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran

Abstract:

Lung cancer is known as one of the most common cancers around the world and is one of the main causes of cancer mortality. Histologically, lung cancer is divided into Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC) respectively account for 20 and 80 percent of all lung cancers. One involving gene in NSCLC pathology is thyroid transcription factor-1 (TTF-1) or NK2 Homeobox 2-1 (NKX2-1) which is a homeobox-containing transcription factor. Recently, researchers have found out that micro RNAs may have regulatory effects on this gene. In addition, an increased level of NKX2-1 protein has been observed in NSCLC patients. Therefore, in this study the differences in new regulatory micro RNAs against NKX2-1 gene would be analyzed in the tissues of NSCLC patients and it would be compared to control individuals. Accordingly, the expression levels of target miRNAs would be determined using qPCR with specific primers. Laboratory investigations of this study is to be done and hopefully, the results can be a great help in detection and treatment of patients suffering this catastrophic disease, as well as base for future researches.

Keywords:

Lung Cancer, NSLC، Micro RNA، Real-Time PCR

Perma Link

https://www.civilica.com/Paper-CIGS15-CIGS15_163.html
COI code: CIGS15_163

how to cite to this paper:

If you want to refer to this article in your research, you can easily use the following in the resources and references section:
Mokhtari, Mohammad & Seyed-Morteza Javadirad, 2018, An Evaluation on Regulatory Role of Micro RNAs on NKX2-1: A Responsible Gene in Lung Cancer, The Third International and 15th National Genetics Congress, تهران, انجمن علمي ژنتيك ايران, https://www.civilica.com/Paper-CIGS15-CIGS15_163.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Mokhtari, Mohammad & Seyed-Morteza Javadirad, 2018)
Second and more: (Mokhtari & Javadirad, 2018)
For a complete overview of how to citation please review the following CIVILICA Guide (Citation)

Scientometrics

The University/Research Center Information:
Type: state university
Paper No.: 13180
in University Ranking and Scientometrics the Iranian universities and research centers are evaluated based on scientific papers.

Research Info Management

Export Citation info of this paper to research management softwares

New Related Papers

Iran Scientific Advertisment Netword

Share this paper

WHAT IS COI?

COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.