A Case of D Alloimmunization in Pregnancy: Successfully Treated Solely with Therapeutic Plasma Exchange (TPE)
Publish place: 15th International Congress of Women and Obstetrics of Iran
Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
COBGY15_265
تاریخ نمایه سازی: 11 آبان 1398
Abstract:
One of the most common causes of fetal anemia is red cell alloimmunization. The standard treatment in fetuses with anemia is intrauterine transfusion (IUT); but this approach may have adverse effects, or sometimes it is not available or even possible. Therefore, immune modulating approaches such as therapeutic plasma exchange (TPE) and the use of intravenous immunoglobulin should be implemented to avoid or delay IUT. We report here the successful management of a case of D alloimmunization in pregnancy solely with TPE, without the need for IUT. The patient was a 33-year-old G4, L2, and D1, who had a history of alloimmunization in her previous pregnancy. TPE was initiated at 17 weeks gestation and was repeated weekly. Altogether, 20 times of plasma exchange were performed and a normal fetus was delivered at week 37
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Authors
Fatemeh Tara
Fellowship of perinatology- Mashhad university of medical sciences- Mashhad- Iran
Asieh Maleki
Fellowship of perinatology- Mashhad university of medical sciences- Mashhad- Iran
Nayereh Taheri
Fellowship of perinatology- Mashhad university of medical sciences- Mashhad- Iran
Somayeh Moein Darbari
Fellowship of perinatology- Mashhad university of medical sciences- Mashhad- Iran