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Comparison of the Serum Level of Venous Endothelial Growth Factor (VEGF) in Normal Pregnant Women and Women with Placenta Accreta Spectrum,2017-2018

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Year: 2019
COI code: DTOGIMED03_123
Paper Language: English

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Authors Comparison of the Serum Level of Venous Endothelial Growth Factor (VEGF) in Normal Pregnant Women and Women with Placenta Accreta Spectrum,2017-2018

  Azam Faraji - Maternal-fetal medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  Nasrin Asadi - Maternal-fetal medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Homeira Vafaei -
Maryam Kasreian -
Shima Bahrami -

Abstract:

Background and Aim : We designed this study to comparison of the serum level of Venous Endothelialgrowth factor (VEGF) in normal pregnant women and women with placenta accrete spectrumMethods : In this case-control study, we studied 45pregnant women in gestational ages of 28-34 weekswith pathological confirmation of placenta accreta spectrum and 46 gestational aged matched healthypregnant women from 2017 to end of 2018 that were under follow up of obstetrics clinics of ShirazUniversity of Medical Sciences and terminate in their hospitals. According to pathology reports of placentawe divided all cases to placenta accrete, precreta and increta. 3 cc blood samples from all participitantswere collected and serum level of VEGF by ELISA kit assayed. Collected data were entered to SPSSVersion 21.0 software. The level for statistical significance was set at 0.05.Results : The results showed that there was a significant increase in the gravidity, number of cesareansection, maternal age, in the placenta accrete, placenta increta, and placenta percreta groups compared tothe normal pregnancy group (p<0.001). There was no significant difference in the serum VEGFconcentration in placenta previa and no previa groups (p=0.248).Conclusion : in our study there is not any significant relationship between placenta accreta and normalplacental group detected. But the mean ranges of plasma level of VEGF in accrete group were higher thannormal group. Maybe larger study need for confirmation of the role of VEGF in pathogenesis of placentaaccrete spectrum.

Keywords:

placenta accreat, placenta previa, placenta increta, VEGF

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Faraji, Azam; Nasrin Asadi; Homeira Vafaei; Maryam Kasreian & Shima Bahrami, 2019, Comparison of the Serum Level of Venous Endothelial Growth Factor (VEGF) in Normal Pregnant Women and Women with Placenta Accreta Spectrum,2017-2018, 3rd debatable topics on obstetrics gynecology & infertility, تهران, دانشگاه علوم پزشكي و خدمات بهداشتي و درماني شهيد بهشتي, https://www.civilica.com/Paper-DTOGIMED03-DTOGIMED03_123.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Faraji, Azam; Nasrin Asadi; Homeira Vafaei; Maryam Kasreian & Shima Bahrami, 2019)
Second and more: (Faraji; Asadi; Vafaei; Kasreian & Bahrami, 2019)
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Type: state university
Paper No.: 16015
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