The effect of Vasopressin during Hysterescopic myomectomy in patients with submucosal myoma; a randomized controlled trial

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:

DTOGIMED03_202

تاریخ نمایه سازی: 26 بهمن 1398

Abstract:

Background and Aim : to assess the effect of vasopressin in reducing the time of surgery, amount ofbleeding and fluid deficit.Methods : This study was conducted as a single-blinded clinical trial on the premenopausal women rangedfrom 18-62 years old. A number of 71 patients were randomly assigned to each arm of study according torandom consecutive numbers. The first group (n= 42) of patients underwent conventional hysterescopicmyomectomy without vasopressin and the second group (n=29) underwent hysterescopic myomectomywith the injection of dilute vasopressin. Measured outcomes were time for myomectomy, fluid deficit,inflow volume, visual clarity and post-operation Hb.Results : The mean time of myomectomy was 38.1 and 77.38 minutes in Vasopressin and control group,respectively (P-value<0.001). The mean inflow volume was 2800 and 4100 in Vasopressin and controlgroup, respectively (P-value=0.029). The visual clarity score was 8.5 and 6.5 in the Vasopressin and controlgroup, respectively (p value<0.001).Conclusion : the injection of vasopressin during Hysterescopic myomectomy is effective in themanagement of fluid deficit, time of surgery and improvement of visual clarity.

Authors

Sara Haghshenas

Department of genecology and obstetrics, school of medicine, university of medical sciences, Isfahan, Iran

Safoura Rouholamin

Department of genecology and obstetrics, school of medicine, university of medical sciences, Isfahan, Iran