Blood Glucose Control Algorithms for Diabetics

A method for optimal continuous insulin therapy for diabetic patients has been sought since the early 1970s. Although technical and medical advances have been made, a fully automated artificial pancreas to replace the functions of the natural organ is still a research aim. This equipment is supposed to be capable of maintaining normal blood glucose level on a desired level and taking all factors affecting glucose concentration into account without inducing hypoglycemia and hyperglycemia. In this paper, an overview of some control algorithms which aim to close the loop for blood glucose control in diabetic patients is given. The focus of this overview is on control algorithms that are expected to be applied in clinical studies in a relatively short term.

Keywords:

Artificial Pancreas , glucose control , proportionalintegral- derivative (PID) , fuzzy logic , model predictive control (MPC)