COI code: HBHEAITH06_018
Paper Language: English
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Authors Effect of Nigella sativa (Black seed) supplementation on glycemic control: A systematic review and meta-analysis of clinical trialsHamed Mohammadi - Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Gholamreza Askari - Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Sepide Talebi - Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:This study was aimed to quantify the anti-hyperglycemic effect of Nigella sativa (N. sativa). An in-depth search to identify clinical trials investigating the impact of N. sativa on glycemic indices via MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Library and Google scholar databases were performed up to November 2018. We used a random effects model to estimate pooled effect size of fasting plasma glucose (FPG), postprandial blood Glucose (PPBG), and hemoglobin A1C (HbA1C).A total of 17 RCTs investigating the effects of N. sativa on FPG, PPBG and HbA1C were included. Meta-analysis suggested a significant association between N. sativa supplementation and reduction in FPG (weighted-mean-difference [WMD]: -9.93 mg/dl, 95%CI: -13.44, -6.41), PPBG (WMD: -14.79 mg/dl, 95% CI: -24.19, -5.39), and HbA1C (WMD: -0.57%, 95% CI: -0.77%, -0.37). Subgroup analysis revealed that N. sativa oil was more effective than N. Sativa powder in reduction of FPG.To sum up, N. sativa consumption have a significant lowering effect on glycemic status. Further studies with prolonged durations and powerful design are needed to specify the exact mechanism, optimal dosage and duration of N. sativa supplementation to obtain a beneficial effect on glycemic status.
Keywords:Nigella Sativa, Fasting Blood Sugar, Glycemic Control, Meta-Analysis
COI code: HBHEAITH06_018
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Mohammadi, Hamed; Gholamreza Askari & Sepide Talebi, 2019, Effect of Nigella sativa (Black seed) supplementation on glycemic control: A systematic review and meta-analysis of clinical trials, The sixth national Conference of Medical Herbs Conventional Medicine and Organic Agriculture, همدان-مركز تحقيقات و آموزش كشاورزي ومنابع طبيعي استان همدان, انجمن علمي پژوهشي دانش پژوهان بوعلي سينا - مركز تحقيقات آموزش كشاورزي ومنابع طبيعي استان همدان, https://www.civilica.com/Paper-HBHEAITH06-HBHEAITH06_018.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Mohammadi, Hamed; Gholamreza Askari & Sepide Talebi, 2019)
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Type: Medical University
Paper No.: 3147
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