COI code: HBHEAITH06_050
Paper Language: English
How to Download This Paper
For Downloading the Fulltext of CIVILICA papers please visit the orginal Persian Section of website.
Authors Isolation of 17 Antidiabetic Compounds from Two Iranian PlantsHossein Dehghan - Medicinal Plants Research Center, Shahed University, Tehran, Iran
Abstract:The present study was aimed to investigate antidiabetic activities of Allium paradoxum, Buxus hyrcana, Convolvulus persicus, Eryngium caucasicum, Heracleum persicum, Pimpinella affinis, Parrotia persica, Primula heterochroma, Pyrus boissieriana, Rheum turkestanicum, Ruscus hyrcanus, and Smilax excels. In the following, the study was conducted to isolate active phytochemicals of the most potent plants, R. turkestanicum and H. persicum.A sequential extraction method used to obtain n-hexane, ethyl acetate, and methanol extracts of various parts of the plants. DPPH scavenging, α-amylase and α-glucosidase inhibition activities, and total phenolic contents of the extracts were investigated. The active compounds were isolated by column chromatography and identified by 1H-, 13C-, 2D-NMR, EI-MS and single-crystal X-ray diffraction.R. turkestanicum and H. persicum showed significant activities against α-glucosidase enzyme more effective than acarbose, a standard antidiabetic drug. As a result, 17 antidiabetic compounds were isolated from R. turkestanicum and H. persicum. Chrysophanol, physcion, emodin, daucosterol and rhododendrin were isolated from Rheum turkestanicum. Psoralen, bergapten, xanthotoxin, isopimpinellin, angelicin, isobergapten, sphondin, pimpinellin, heratomin, 5-methoxyheratomin, moellendorffiline, and fraxetin were isolated from H. persicum.Consequently, moellendorffiline and daucosterol introduced as new potent antidiabetic compounds, more potent than acarbose, an antidiabetic drug.
Keywords:Iranian plants; Antidiabetic; Antioxidant; Moellendorffiline; Daucosterol.
COI code: HBHEAITH06_050
how to cite to this paper:If you want to refer to this article in your research, you can easily use the following in the resources and references section:
Dehghan, Hossein, 2019, Isolation of 17 Antidiabetic Compounds from Two Iranian Plants, The sixth national Conference of Medical Herbs Conventional Medicine and Organic Agriculture, همدان-مركز تحقيقات و آموزش كشاورزي ومنابع طبيعي استان همدان, انجمن علمي پژوهشي دانش پژوهان بوعلي سينا - مركز تحقيقات آموزش كشاورزي ومنابع طبيعي استان همدان, https://www.civilica.com/Paper-HBHEAITH06-HBHEAITH06_050.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Dehghan, Hossein, 2019)
Second and more: (Dehghan, 2019)
For a complete overview of how to citation please review the following CIVILICA Guide (Citation)
The University/Research Center Information:
Type: state university
Paper No.: 3839
in University Ranking and Scientometrics the Iranian universities and research centers are evaluated based on scientific papers.
Research Info Management
Export Citation info of this paper to research management softwares
New Related Papers
- Proteomic response of sensitive cultivar of canola to Pseudomonas fluoresense FY32 under saline condition
- Assessment and Spatial Variability of Groundwater Resources for Corrosiveness and Scaling Potential in North of Qazvin Plain, Iran
- Comparative effects of chitosan and SiO2 nanoparticles on seed germination of barley (Hordeum vulgare L.)
- Efficacy evaluation of Beauveria bassiana fungus and Cannabis sativa extract for the control of Amitermes vilis termite
- Assessment of farmers participation in the pattern of the insurance of agriculture crops in hot and dry areas
The Above articles are recently indexed in the related subjects
Iran Scientific Advertisment Netword
Share this paper
WHAT IS COI?
COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.