Analysis The Role of Membrane Transport Proteins in Heart Cancer with the Aim of Diagnosis and Treatment

A heart tumor consists of a lot of grown cells which have been created in an unsuitable location in the heart. When individuals are exposed to known or unknown environmental and genetic factors, disorders happen. These disorders change the expression of genes or a collection of genes which can have an influential role in the creation of genes. With the help of Expressed Sequence Tags (EST), the present study tries to predict and detect the genes that are effective in heart cancer in the cDNA library in the NCBI database. The results showed that ribosome subunit coding genes, especially small subunits, are over expressed in the cancer tissues of heart. In contrast, membrane transport protein genes, like myelin basic protein (MBP), are under expressed in the cancer tissues of heart. The results of this study include an accurate report of genes that are influential in heart tumor. They can be used to better detect the disease and improve the treatment procedure.

Keywords:

Heart Cancer , Expressed Sequence Tags (EST) , Transmembrane Proteins , Bioinformatics