CIVILICA We Respect the Science
Publisher of Iranian Journals and Conference Proceedings

Enhancemnt of in vtro gene transfection by ultrasound

Credit to Download: 1 | Page Numbers 3 | Abstract Views: 1676
Year: 2001
COI code: ICBME10_029
Paper Language: English

How to Download This Paper

For Downloading the Fulltext of CIVILICA papers please visit the orginal Persian Section of website.

Authors Enhancemnt of in vtro gene transfection by ultrasound

Hossein Hosseinkhani - Dept. of Tissue Engineering, Institute for Frontier Medical Sciences
Yasuhiko Tabata - Kyoto University, Dai-Ichi Seiuonso, 35 Matsugasaki, Higashi-cho, Sakyo-ku, Kyoto, Japan


Introduction of plaasmid DNAs into cells for efficient expression of DNA has been being attempted aiming at creation of genetically engineered cells and gene therapy. Among various methods, viral vectors artificially modified have been used experimentally and clinically because of the high transfection efficiency. However, there are some problems to be improved, i.e., virus toxicity and antigenicity. On the other hand, we cannot always expect satisfiable DNA expression by using non-viral vectors of poor transfection efficiency. One possible way for the efficiency enhancement is to have demonstrated that US exposure enabled plasmid DNA to enhance its transfection efficiency (1,2). It is possible that US physically enhances the permeability of cell membrane, resulting in promoted DNA entry into cells. The objective of this study is to obtain fundamental information about the US-induced enhancement of DNA by use of in vitro cell culture.


Perma Link
COI code: ICBME10_029

how to cite to this paper:

If you want to refer to this article in your research, you can easily use the following in the resources and references section:
Hosseinkhani, Hossein & Yasuhiko Tabata, 2001, Enhancemnt of in vtro gene transfection by ultrasound, 10th Iranian conference on Biomedical Engineering, تهران, انجمن مهندسي پزشكي ايران, دانشگاه تربيت مدرس, the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Hosseinkhani, Hossein & Yasuhiko Tabata, 2001)
Second and more: (Hosseinkhani & Tabata, 2001)
For a complete overview of how to citation please review the following CIVILICA Guide (Citation)

Research Info Management

Export Citation info of this paper to research management softwares

New Related Papers

Iran Scientific Advertisment Netword

Share this paper


COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.