Preparing nanocomposite fibrrous scaffolds of P3HB /nHA for Bone tissue engineering
Publish place: 17th Iranian Conference on Biomedical Engineering
Publish Year: 1389
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICBME17_230
تاریخ نمایه سازی: 9 تیر 1392
Abstract:
Nanocomposites are recently known to be among the most successful materials in biomedical applications. In this work we sought to fabricate fibrous scaffolds which can mimic the extra cellular matrix of cartilaginous connective tissue not only to a structural extent but with a mechanical and biological analogy. Poly(3-hydroxybutyrate) (P3HB) matrices were reinforced with 5, 10 and 15 %wt hydroxyapatite (HA) nanoparticles andelectrospun into nanocomposite fibrous scaffolds. Mechanical properties of each case were compared with that of a P3HB scaffold produced in the same processing condition. Spectroscopic and morphological observations were used for detecting the interaction quality between the constituents. Nanoparticles rested deep within the fibers of 1
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Authors
Ashkan Heidarkhan Tehrani
Department of Textile Engineering, Isfahan University of Technology, Isfahan
Ali Zadhoush
Department of Textile Engineering, Isfahan University of Technology, Isfahan
Saeed Karbasi
Medical Physics and Biomedical Engineering Group, Department of Medicine, Isfahan University of MedicalSciences, Isfahan