Preparing nanocomposite fibrrous scaffolds of P3HB /nHA for Bone tissue engineering

Publish Year: 1389
نوع سند: مقاله کنفرانسی
زبان: English
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ICBME17_230

تاریخ نمایه سازی: 9 تیر 1392

Abstract:

Nanocomposites are recently known to be among the most successful materials in biomedical applications. In this work we sought to fabricate fibrous scaffolds which can mimic the extra cellular matrix of cartilaginous connective tissue not only to a structural extent but with a mechanical and biological analogy. Poly(3-hydroxybutyrate) (P3HB) matrices were reinforced with 5, 10 and 15 %wt hydroxyapatite (HA) nanoparticles andelectrospun into nanocomposite fibrous scaffolds. Mechanical properties of each case were compared with that of a P3HB scaffold produced in the same processing condition. Spectroscopic and morphological observations were used for detecting the interaction quality between the constituents. Nanoparticles rested deep within the fibers of 1

Authors

Ashkan Heidarkhan Tehrani

Department of Textile Engineering, Isfahan University of Technology, Isfahan

Ali Zadhoush

Department of Textile Engineering, Isfahan University of Technology, Isfahan

Saeed Karbasi

Medical Physics and Biomedical Engineering Group, Department of Medicine, Isfahan University of MedicalSciences, Isfahan