Analytical Study on the Turbaulent shear-induced hemolysis and platelet activation downstream of mechanical heart valves
Publish place: 18th Iranian conference on Biomedical Engineering
Publish Year: 1390
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICBME18_080
تاریخ نمایه سازی: 27 فروردین 1393
Abstract:
Mechanical heart valves (MHVs) are widely implanted to replace the diseased heart valves. The performance of these valves strongly is limited by complications such as hemolysis and platelet activation. Abnormal flow patterns and turbulence generated by MHVs are the major reasons of these problems. Thus a better understanding of MHV hemodynamics is very important. In the present study, a simplified analytical approach is proposed to predict turbulent shear-induced hemolysis and platelet activation downstream of mechanical hear valves. This theoretical model was validated with such available in vivo experimental results where a good agreement was found. Therefore the present model provides a new insight into the behavior of turbulent Reynolds stresses downstream of the various mechanical heart valves and estimates them accurately without any extra computational or experimental cost.
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