A new approach to model subarachoid trabeculae resistance in cerebrospinal fluid flow
Publish place: 19th Iranian conference on Biomedical Engineering
Publish Year: 1391
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICBME19_089
تاریخ نمایه سازی: 9 بهمن 1392
Abstract:
The subarachnoid space (SAS) contains cerebrospinal fluid (CSF) and a variety of trabeculae that are arranged between the arachnoid mater and the pia layers of the meninges, which stabilizes the shape and the position of the brain during head movements. The complex geometry of subarachnoid trabeculae makes it extremely challenging for the researchers to model the role of them in cerebrospinal fluid (CSF) flow. The goal of this research is to investigate the role of subarachnoid trabeculae in CSF flow, and introduce an alternative model. Three fluid models were created: 1) a model with normal CSF properties, 2) a model with an equivalent fluid, and 3) a modified model having trabeculae as some flow-obstacles. It is found that the trabeculae yield smoother pressure response in a head impact simulation. The sudden pressure changes in SAS are mainly caused by the improvement of the trabeculae anatomy. The study showed that the presence of trabeculae should not be ignored, and the modified model could be used to show heterogeneous distribution of trabeculae in SAS.
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Authors
Mahsa Ghaffari
Biomedical Engineering Department Amirkabir University of Technology
Mohammad Zoghi
Farmingdale State College The State University of New York (SUNY)
Mostafa Rostami
Biomedical Engineering Department Amirkabir University of Technology
Nabiollah Abolfathi
Biomedical Engineering Department Amirkabir University of Technology