synthesis of oxindoles using nano-MgAl2O3 as a novel and efficient catalyst

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:

ICCO02_190

تاریخ نمایه سازی: 3 اردیبهشت 1399

Abstract:

Oxindole and their derivatives are of considerable interest as they possess a wide range of biological properties [1], such as spasmolytic, diuretic, anticoagulant, anticancer and antianaphylactic activity [2]. In addition, they can be used as cognitive enhancers, for the treatment of neurodegenerative diseases, including Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, Parkinson’s disease, AIDS associated dementia and Down’s syndrome as well as for the treatment of schizophrenia and myoclonus [3].As part of our program aimed at developing new selective and environmental friendly methodologies for the preparation of fine chemicals, herein, we report the synthesis of Oxindole using nano-MgAl2O3 in good yields.

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Authors

Bita Baghernejad

Department of Chemistry, School of Sciences, Payame Noor University(PNU), ۱۹۳۹۵-۳۶۹۷, i.r. of Iran

Atefe Zakariaie

Department of Chemistry, School of Sciences, Payame Noor University(PNU), ۱۹۳۹۵-۳۶۹۷, i.r. of Iran