Investigating Healing Effects of Pot Marigold Oil and ProsopisFarcta Extract on Skin Lesions in Rats

It has been a common practice to use herbal plants in Iran and other countries around the world since past years. Today with unfavorable impacts and side effects of chemical drugs, traditionalmedicine and prescription of herbal plants have attracted specific attention. Treatment and healing of lesions can be considered among major issues which human has faced from the first of creation. Using pot marigold oil and powder of ProsopisFarcta fruit has been long common in Iran for treatment of skin lesions. Therefore, the present study aims to investigate quick healing and restoration effects of ProsopisFractafruit extract as well as pot marigold oil on laboratory rats. The research was a laboratory trial which was done on 05 rats which were divided randomly into five groups including ten rats after complete anesthesia and creating spinal injuries in completely similar conditions and characteristics. For treatment, five interventions were used as follows: 1. Normal saline solution (59.0 physiologic serum); 2. ProsopisFracta fruit extract (with density of 590 to ..900 solvent); 3. Pure pot marigold oil; 4.Combination of ProsopisFracta fruit extract and pot marigold oil (.00 oil and 5900 extract); and 0.Nitroforazone 10 ointment (positive control). Features including 1. Rats' body temperature, 2.Testing injury site blood, 3.Lesion extent, 4.Histology microscopic experiment during sixteen days of treatment were measured and collected data were analyzed using SPSS statistical software by mean+-SEM as well as survival analysis tests at significance level of 5950. According to the results, intervention by combination of ProsopisFracta fruit extract and pot marigold oil is significantly better regarding all features studied, while given the feature of lesion extent it shows a significant difference in treatment and healing of the lesion. Results of a study done by NakhaiMoghadam and colleagues confirm the results obtained by the present study.

Keywords:

laboratory rats , lesion , healing , ProsopisFracta , pot marigold