HN-00510037_The Effects of Taurine Supplementation on Hematological Markers in Patients with Traumatic Brain Injury

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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ICNC03_057

تاریخ نمایه سازی: 12 اسفند 1398

Abstract:

Introduction: Hematological abnormalities after traumatic brain injury (TBI) are common, and are associated with poor outcome. The aim of this study was to evaluate the hematological effects of Taurine supplementation, as an antioxidant, in patients with traumatic brain injury (TBI).Methods: Thirty-two patients with TBI (GCS = 6-9) were randomized into treatment and control groups. The treatment group received 30 mg/kg/day of Taurine in addition to the Standard Entera Meal, while the control group received Standard Entera Meal for 14 days. Red blood cell (RBC) count, white blood cell (WBC) count, hemoglobin (Hb), hematocrit (Hct) and platelet count (Plt) were assessed at baseline and at the end of intervention. Data was analyzed using SPSS software (version 13.0). The two-sided significance level was considered p<0.05.Results: Taurine increased Hct (7.2±17.8 vs. -0.6±5.3, p= 0.1) and prevented the increase in WBC (0.76±4 vs. 1.5±4.7, p=0.999). Taurine supplementation also prevented further reduction in Hb (-0.31±3.2 vs. -0.6±2.04, p=0.754) and RBC (-0.06±0.94 vs. -0.16±0.75, p=0.892), but these differences were not statistically significant (p> 0.05).Conclusion: According to the results of the present study, Taurine had no effect on hematological markers.