HN-00690036_The Effects of Bunium Persicum Supplementation on General and Central Obesity in Patients with Type 2 Diabetes: A Double-Blind Randomized Placebo-Controlled Clinical Trial

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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ICNC03_066

تاریخ نمایه سازی: 12 اسفند 1398

Abstract:

Introduction: Overweight and obesity are the most common risk factors for type 2 diabetes mellitus. Our aim was to investigate the effects of bunium persicum (BP) on Waist circumference (WC), body mass index (BMI) and Nesfatin-1 among overweight or obese T2DM patients.Methods: The place of participant recruitment was the diabetic clinic of Bo’Ali hospital in Zahedan. Based on the eligibility criteria, 60 participants were randomly divided into two groups as BP (n=30) or placebo (n=30). The supplementation was one 1000 mg capsules 2 times/day with launch and dinner for 3 months. Weight, height and waist circumference (WC) were measured. Body mass index (BMI) was also calculated.Results: In comparison with placebo, PB significantly decreased WC and BMI (P<0.05). After adjustment for confounders, the changes were similar (P<0.05). The differences in Nesfatin-1 were not significant (P> 0.05).Conclusion: PB supplement improved body BMI and WC among overweight or obese T2DM patients; though, further trials are suggested to confirm results.Trial Registration: Iranian Registry of Clinical Trials (IRCT) number IRCT20181207041876N1, 18/01/2019.

Authors

Saber Jafari-Maskouni

MSc Student, Department of Nutrition, Faculty of Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran

Somayeh Asghari

Department of Medical Laboratory Sciences, Faculty of Medical Sciences, Zahedan University of Medical Sciences, zahedan, Iran

Mansour Shahraki

۳Ph.D, Assotiate Professor, Department of Nutrition, Faculty of Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Sistan and Baluchestan

Mahmoud Ali Kaykhaei

PhD, Assotiate Professor, Department of Internal Medicine, Faculty of Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran

Alireza Dashipour

PhD, Assotiate Professor, Department of Food Sciences and Nutrition, Faculty of Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran