HN-01780137_Association of Severity of Disease and Adequate Intake of Protein and Calories in Critically Ill Patients at Imam Reza Hospital (2018), Mashhad, Iran

Introduction: Malnutrition is a major problem in patients admitted to the intensive care unit (ICU). APACHE II score is the most acceptable scoring system of disease severity and predictor of mortality in ICU patients. The aim of this study was to find an association between severity of disease and amount of calorie and protein intake in critically ill patients.Methods: We collected data from 70 patients. Severity of disease was calculated based on Acute Physiology and Chronic Health (APACHE) scoring system. We measured Energy and protein requirement. The required energy and protein values were compared with the provided values. Protein and caloric content of gavage solution was analyzed with Leen ion, Gerber and Kejeldal methods. Data were analyzed with paired sample t-test in SPSS version 25.Results: Correlation of disease severity and difference between required and provided calorie was r= 0.336, P= 0.07 and with difference between required and provided protein was r=0.374, P=0.04. Discharged Patients had lower differences between received and required calorie compared to dead patients (-1100.8 212.2 vs. - 912.2± 29.5, P= 0.32). The results was somewhat similar for protein (-65.4 ±19.1 in discharged one vs. -54.5± 13 in dead patients, P= 0.54).Conclusion: This study shows that there was a direct association between severity of disease according to APACHE II score and inadequate intake of calorie and protein.

Keywords:

Disease severity , Calorie , Protein , critically ill patient