Sonochemical synthesis and characterization of some new four coordinated cadmium complexes: New precursors for nanostructure metal oxides, antimicrobial, and DNA cleavage potential

Schiff bases represented a class of compounds having azomethine group (-CH = N‐) and considered as the potential sites for bio‐chemically active compounds that are related to intermolecular hydrogen bonding and proton transfer equilibria [1]. Metal complexes of Schiff base ligands have gained considerable attention as the results of their spectroscopic properties and remarkable antifungal, antibacterial and antitumor activities applications [2].In this work some new cadmium(II) Schiff base complexes CdLX2 (where X = Cl-, Br-, I-, SCN-, N3-, NO3- and L is a new N2‐Schiff base ligand were synthesized and characterized by fourier transform infrared, proton and carbon nuclear magnetic resonance spectra, UV–visible, thermal analyses, and molar conductivity measurements. cadmium complexes have been also prepared in nanostructure sizes under ultrasonic irradiation confirmed by X‐ray powder diffraction (XRD) and the morphology and size of ultrasound-assisted synthesized cadmium complex have been investigated using scanning electron microscopy (SEM). CdO nanoparticles were prepared by direct calcination process of cadmium iodide complex at 600°C under air atmosphere. antibacterial/antifungal activities of the compounds were screened by the disk diffusion method against the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa, the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis and the fungi strain Aspergillus oryzaeand Candida albicans. The antimicrobial activities were determined for all compounds and the complexation was found to enhance the inhibitory activity. Moreover, DNA cleavage potential of all compounds was investigated by agarose gel electrophoresis method. The results showed remarkable ability of some cadmium complexes for DNA cleavage.