Synthesis and characterization of molecular-crystal structure of a coordination complex based on zinc and pyridine-2,5-dicarboxylic acid N-oxide

Chemistry of coordination compounds is an interesting and growing field of research; design and construction of novel compounds with favorable properties have fascinating applications ranging from nanotechnology, catalysis, macromolecular crystallography and medicine. O-donor ligands are of particular interest because their complexes with biologically important metals have potential medical applications. Furthermore, planar and rigid heterocyclic N-donor π-electron-deficient ligands, are widely used in supramolecular chemistry and/or in the molecular biology as DNA cleaving reagents and etc. The aim of the present study is to produce an organized structure possessing a combination of both properties using the mixed ligands. In this work, we select pyridine-2,5-dicarboxyxlic acid N-oxide (pydco) as a versatile O-donor ligand with -COOH groups in a p-arrangement. It can be used to construct coordination polymers or link monomeric or dimeric compounds by hydrogen bonding through its uncoordinated carboxylate group at the position 5 [1-3]. Herein, we report successful preparation of a new coordination complex based on pydco, 2,2 -bipyridine (bpy) and zinc metal, which is characterized by physico-chemical approaches such as elemental analysis (CHN), IR spectroscopy and melting point. Based on our data it may be formulated as [Zn(pydco)(bpy)(H2O)2]·4H2O. This category of complexes remains little-investigated in aspects such as single crystal X-ray diffraction, supramolecular interactions and biological tests; therefore we intend to extend our studies.

Keywords:

Mixed ligands , pyridine-2 , 5-dicarboxylic acid N-oxide , 2 , 2 -bipyridine