Green synthesis of silver nanoparticles using C. verum extract

A number of approaches are available for the synthesis of silver nanoparticles for example, reduction in solutions, chemical and photochemical reactions in reverse micelles, thermal decomposition of silver compounds, radiation assisted, electrochemical, sonochemical, microwave assisted process and recently via green chemistry route [1].Greener syntheses of nanoparticles also provide advancement over other methods as they are simple, one step, cost-effective, environment friendly and relatively reproducible and often results in more stable materials [2]. Traditional drugs available now for oral or injectable administration are not always manufactured as the optimal formulation for each product. Products containing proteins or nucleic acids require a more innovative type of carrier system to enhance their efficacy and protect them from unwanted degradation. It is notable that the efficiency of most drug delivery systems is directly related to particle size. Due to their small size and large surface area, drug nanoparticles show increased solubility and thus enhanced bioavailability, additional ability to cross the blood brain barrier (BBB), enter the pulmonary system and be absorbed through the tight junctions of endothelial cells of the skin. Specifically, nanoparticles made from natural and synthetic polymers have received more attention because they can be customized for targeted delivery of drugs, improve bioavailability, and provide a controlled release of medication [3]. Because of antimicrobial properties and potential application of silver ions in medicine, in this research we have synthesized silver nanoparticles using Cinnamomum verum extract and characterized them using UV-Vis spectroscopy and scanning electron microscopy. Figure 1 shows SEM image of green synthesized silver nanoparticles using C. verum extact, size of these nanoparticles are in the range of 40.3- 81 nanometersand an UV-Vis peak in shows the formation of Ag NPs in figure 2.