ENTERAL FEEDING COMPOSITION AND CLINICAL OUTCOMES IN ACUTE PULMONARY FAILURE PATIENTS

Background and Aim: It has been postulated that high fat diets are appropriate in pulmonary failure but guidelines does not recommend this diet yet. We evaluated effects of two types of high fat formula on clinical outcomes of patients with acute pulmonary failure in intensive care unit (ICU).Methods: This randomized clinical trial was done on 42 patients, admitted to ICU and received enteral feeding. Patients were randomly classified into three diet groups of 14 each. Group A received high protein formula (protein:20%, fat:30%, charbohydrate:50%), group B received high fat formula (protein:20%, fat:45% including half of olive oil and half sunflower oil, charbohydrate:35%) and group C received high olive oil formula (protein:20%, fat:45% including sunflower oil, charbohydrate:35 %). Results: Basal characteristics of subjects were the same. The average SOFA score during the study for assessment of organ failure was not statistically significant between the three groups. Duration of stay in ICU was highest in the group A and lowest in the group B, but the difference was not statistically significant. This finding was also seen for the duration of mechanical ventilation. There was no significant difference between the three groups in mortality rate, but it was higher in group C than in the other two groups, and in group B was not reported any death during the study.Conclusion: High fat diets have no clinical benefits in acute respiratory failure.

Keywords:

Enteral Nutrition , Olive , Ventilation , Mortality