Published in: First Personal Medical Congress
COI code: IPMCMED01_105
Paper Language: English
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Authors applications of nanotechnology to solve challenges of cardiac tissue engineeringNarges Esmaeilzadeh - Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
Ehteram Hosseinzadeh - Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
Abstract:Cardiovascular diseases are the highest cause of mortality in the world. Cardiomyocytes (cardiac muscle cells) have limited proliferation, therefore repair of the damaged tissue will not occurred and necrosis or fibrosis tissue will be replaced. Myocardial mass loss and lack of contractility are precursors to heart failure. Nowadays, medication, surgery and heart transplantation are methods that used for treatment of these diseases. Tissue engineering is an interdisciplinary field that help to treat medical problems such as tissue loss or severe organ failure. Despite all the progress made in this field over the last few years, there is still some limitations such as delivering nutrients to cells, defects in cellular function and immune response to engineered scaffolds. These limitations are greatly affected by nanotechnology.Nanotechnology is the development of new systems that mimic natural tissue complex structure and boost cellular signal, attachment, cell growth and differentiation. nanotechnology in cardiac tissue engineering help to precise control over the engineered constructions and enhance the mechanical and electrical properties of the cardiac patches. Scaffolds with Gold nanoparticles promote massive cardiac sarcomeric actinin expression, significantly higher contraction amplitudes and rates.
Keywords:cardiac tissue engineering- nanotechnology- nano particle- cardiomyocyte
COI code: IPMCMED01_105
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Esmaeilzadeh, Narges & Ehteram Hosseinzadeh, 2016, applications of nanotechnology to solve challenges of cardiac tissue engineering, First Personal Medical Congress, تهران, دانشگاه علوم پزشكي ايران - پژوهشكده ملي مهندسي ژنتيك و زيست فناوري ايران، مركز همكاري هاي فناوري و نوآوري هاي رياست جمهوري, https://www.civilica.com/Paper-IPMCMED01-IPMCMED01_105.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
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The University/Research Center Information:
Type: Medical University
Paper No.: 2969
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