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Investigation of the mitochondrial haplogroups in a selective population of Isfahan province

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Year: 2016
COI code: IPMCMED01_180
Paper Language: English

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Authors Investigation of the mitochondrial haplogroups in a selective population of Isfahan province

Elham Iranpour - mobarakeh
Massoud Houshmand - Supervisor

Abstract:

In order to investigate the mitochondrial haplogroups in a selective population of Isfahanprovince, 96 unrelated men in Isfahan province with at least two generations in this provincewere token blood. Then DNA was extracted and quality assessed. 25 coding SNPs definingthe major haplogroups that occur in Africa, Western Eurasia and Eastern Eurasia wereselected and combined into two multiplex genotyping assays. Each one consisting of a PCRstep and a SNaPShot step. Then for support of our detective haplogroups by SNaPShotsystem, D-Loop region was sequenced in some samples. : In this province Western Eurasianhaplogroups were predominant. Haplogroup U and H (23%, 22%) and then T, J and U8b(11%, 10% and 7%) had the most frequency. Eastern Eurasian haplogroups were present at alower frequency of 5% (C, D, R9, M and N).

Keywords:

mtDNA, SNP, Haplogroup, Isfahan province

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COI code: IPMCMED01_180

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Iranpour, Elham & Massoud Houshmand, 2016, Investigation of the mitochondrial haplogroups in a selective population of Isfahan province, First Personal Medical Congress, تهران, دانشگاه علوم پزشكي ايران - پژوهشكده ملي مهندسي ژنتيك و زيست فناوري ايران، مركز همكاري هاي فناوري و نوآوري هاي رياست جمهوري, https://www.civilica.com/Paper-IPMCMED01-IPMCMED01_180.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
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