Studying the relation of blood lead level with the thyroid hormone concentrations and blood cell count

Background and Purpose: Lead has many applications in the industry but does not play a specific physiological role in the body. According to performed studies, lead has an undesirable effect on the nervous, gastrointestinal, respiratory, and endocrine systems. People who are highly exposed to this element, due to their occupation or living place, are affected by its harmful effects. The aim of this study was to evaluate the level of thyroid hormones and blood cells in people highly exposed to lead.Analysis method: This cross-sectional study was carried out on 37 patients with high exposure level to lead in Tehran. After filling out the consent form and questionnaire, the blood samples were collected from them and their levels of blood lead, thyroid hormones and blood parameters were evaluated in a laboratory. Normal distribution of data was assessed by Kolmogorov Smirnov test by Med Calc 14.8.1.Results: Obtained results demonstrated that there was no significant association between blood lead levels and levels of thyroid hormones, number of blood cells and related blood cells parameters (HCT, HGB, MCV, MCH and MCHC) in this study. However, according to Kolmogorov Smirnov test by Med Calc 14.8.1, there was a weak link between blood lead levels and age (r = 0.25).Conclusion: High lead levels did not affect the level of the thyroid hormones, the number of blood cells and the levels of the red blood cells parameters in this cross-sectional study

Keywords:

Lead , Thyroid hormones , Red blood cells , White blood cells , Platelets , Hemoglobin , Hematocrit