Electrochemical determination of bisphenol A using a cobalt oxide sensor

Bisphenol A (BPA), one of the important organic compounds, is widely used in the industrial production such as plastic bottles, baby bottles, children s toys, and also the inner surface coating of cans used for food. BPA exhibits weak estrogenic transcriptional activities and potentially interferes with the endocrine system of both the wildlife and humans. Several analytical methods, have been employed for determination of BPA such as high-performance liquid chromatography, fluorescence, gas chromatography, liquid chromatography-mass spectrometry and electrochemical detection. Among them, electrochemical methods were regarded because fast response, portability, simplicity for operators and low cost.In this work, we used a laminate nanocomposite based on multiwall carbon nanotubes (MWCNTs) and Co3O4 nanorode at the surface of a glassy carbon electrode for BPA detection. The electrooxidation of BPA molecules was monitored by cyclic voltammetry (CV) and differential pulse voltammetry (DPV), It was found that the proposed sensor improves the oxidation of BPA at the modified electrode surface compared to the bare electrode more than ten times. The results of the analyses showed that the fabricated sensor had a good linear range (0.01–100 μM) and a low detection limit (3.1 nM). The obtained results revealed high selectivity of the method which provides determination of BPA in a wide variety of real samples.