Application of Lanthanum Ferrite nano particle in the synthesis of diindolyl-oxindoles

This study focuses on nano-LaFeO3 particles as nanocatalyst for the synthesis of diindolyl-oxindoles,an important class of potentially bioactive compounds.The oxindole derivatives were prepared by the condensation of indole and isatin compounds in water, an excellent solvent in terms of environmental impact and reduction waste production [1]. The vast majority of catalysts used in modern chemical industry are based on mixed metal oxides including perovskite oxides ABO3, where A is a rare-earth element, B is 3d transition metal remain prominent Also, perovskite oxides crystals can have broad applications in advanced technologies such as solid oxide fuel cells, catalysts and chemical sensors, magnetic materials, electrode materials, etc [2]. One of most common perovskite oxides, LaFeO3 nanocrystal is a very known material and thus has received intensive investigations over years [3]. In the among tested temperature and the amount of catalyst, the condensation of indole and isatin was best catalyzed by 0.008 gr of Nano LaFeO3 at 90 ℃ as the reaction was completed within a high yield (93-98%).