Study of Antioxidant Activity of Methanolic Extract of (Inula Salicina (L.)) and (Inula Thapsoids (M.B.ex Willd)) With FRAP and DPPH Methods

Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:

ISOC26_032

تاریخ نمایه سازی: 2 شهریور 1398

Abstract:

Antioxidant compounds are very important in human life. Antioxidants are the main factorsfor neutralizing the free radicals which are active and harmful for human. Preparing antioxidationresources to reduce the effects of oxidation stress is important [1,2]. Thus, this researchwas carried out to study the antioxidation properties of metanolic extracts of Inula salicina(L.) and Inula thopsoides (M.B. ex Willd). In this laboratory study, the plants were collectedfrom North Khorasan Province of Iran, in spring of 2017 and the metanolic extract from aerialparts of plants was prepared by maceration extraction method. the antioxidant activities of thesamples were determined by two different test systems, namely, DPPH free radical scavengingand iron deficiency reduction (FRAP) methods; and the results were compared with syntheticantioxidant BHT. In this study, IC50 value of the metanolic extracts were obtained 3.217and 4.489 mg.mL-1 of Inula salicina (L.) and Inula thopspides(M.B.ex Willd) respectively,whiles this value was 0.116 mg mL-1 for synthetic antioxidant (BHT). Also, the reducingpower of extracts reported 1199.68 and 945.33 (mmol of Fe+2/ mg extract) for Inula salicina(L.) and Inula thopsoides (M.B. ex Willd) respectively.The results show that the Inula Salicina L. plant has an antioxidant effect on the Inula Thapsoids(M.B. ex Willd) but the methanolic extract both significantly less antioxidant than theBHT positive control. The results of extraction efficiency and antioxidant properties of theextracts are presented in the table below.

Authors

Ali Firouznia

Department of Chemistry, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran

Fahimeh Doustzadeh

Department of Chemistry, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran

Gholamreza Zivari

Department of Chemistry, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran