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Injectable hydrogels for myocardial tissue regeneration

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Year: 2018
COI code: ITERMED01_034
Paper Language: English

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Authors Injectable hydrogels for myocardial tissue regeneration

  Hadis Torabi - Department of Biomedical engineering, Faculty of Engineering, University of Isfahan, Isfahan, Iran
  Mehdi Mehdikhani - Department of Biomedical engineering, Faculty of Engineering, University of Isfahan, Isfahan, Iran


Cardiovascular diseases and myocardial infarction are counted as the major causes of mortality around the world. Not treating the damaged part of the heart due to myocardial infarction, within a few years, can result in total heart failure. Different approaches, such as medication, invasive treatment and finally heart transplant have been used until now, however, injectable hydrogels can provide a combination of cell therapy and medication in a minimally invasive way. Utilization of natural and synthesized polymers which are sensitive to special stimuli such as temperature, pH and UV radiation together are an appropriate solution for producing injectable hydrogels for the purpose of creating the expected mechanical and biological features. Choosing the type of biomaterials, however, is one of the main challenges. Optimizing the compound of hydrogel together with electrical properties can create unique features to be used for myocardial tissue engineering. This research addressed the several types of injectable hydrogels that can be used in myocardial tissue engineering based on the type of their stimulus and various approaches in order to generate electrical properties in hydrogels. Injectable hydrogels have not reached the level to be used clinically in minimally invasive treatments for rebuilding myocardial tissue of the heart, however, hopefully this would be realized in near future, and result in the treatment of the patients and less mortality.


Injectable hydrogels, Physical cross linking, Cardiac regeneration, Conductive hydrogels, Myocardial tissue engineering

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COI code: ITERMED01_034

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Torabi, Hadis & Mehdi Mehdikhani, 2018, Injectable hydrogels for myocardial tissue regeneration, 1st International Iranian Tissue Engineering and Regenerative Medicine Congress (ITERM2018), تهران, انجمن علمي مهندسي بافت و بازسازي ايران, the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Torabi, Hadis & Mehdi Mehdikhani, 2018)
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The University/Research Center Information:
Type: state university
Paper No.: 13242
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