Advance drug delivery technologyand targeting in whole organs and tissues

IntroductionDrug delivery refers to the utilized to present the drug to the desired body site for drug release and absorption, or the subsequent transport of the active ingredients across the biological membranes to the site of action. This technology offers significant benefits to pharmaceuticals such as reduction in dosing frequency and side effects and the extension of patient life. In addition, drug delivery technology allows the use of alternate routes for the administration of drugs that can improve patient compliance and convenience (oral instead of injectable).ObjectiveThis study is evaluated progress drug delivery technology and targeting in organs and tissuesMethodsWe performed systematic review of literature with related keywords in PubMed, Science direct and Google scholar to gather information in articles published since 2013 and summarized here.ResultsMedications can be taken in a variety of ways by swallowing, by inhalation, by absorption through the skin, or by intravenous injection. The target may be whole organs (heart, lung, brain), tissue types (muscle, nerve), disease-specific structures (tumor cells), or structures inside of cells. Each method has advantages and disadvantages, and not all methods can be used for every medication.There are different kinds of delivery vehicles such as Nanoparticles, Colloidal, liposome-based formulations.ConclusionsResearchers have begun to reformulate drugs so they may be more safely used in specific conditions. The full potential of drug delivery systems extends beyond treatment. By using advanced imaging technologies with targeted delivery, doctors may someday be able to diagnose and treat diseases in one-step, a new strategy called theranostics

Keywords:

Drug delivery , Medicine , Nanoparticles