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Efficacy of Golden Immunstim for Improvement of Abdominal Cramp, Diarrhea, Vomiting, and Fever in Dysenteric Patients: A Randomized Clinical Trial

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Year: 2018
COI code: JR_INJPM-6-5_012
Paper Language: English

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Authors Efficacy of Golden Immunstim for Improvement of Abdominal Cramp, Diarrhea, Vomiting, and Fever in Dysenteric Patients: A Randomized Clinical Trial

  Bahram Ezati - Infectious Diseases Research Center (IDRC), Department of Pediatric, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
  Mohammad Arjomandzadegan - Infectious Diseases Research Center (IDRC), Department of Pediatric, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
  Fatemeh Doreh - Infectious Diseases Research Center (IDRC), Department of Pediatric, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
  Ali Arjmand - Infectious Diseases Research Center (IDRC), Department of Pediatric, School of Medicine, Arak University of Medical Sciences, Arak, Iran.

Abstract:

Background Dysentery is described as a diarrhea with visible blood in the feces. In some regions of world, resistance to antibiotic was reported. Therefore, it is very important to use a safer treatment for this disease. We aimed to survey the efficacy of Golden Immunstim drug on improvement of abdominal cramp, diarrhea, vomiting, and fever in dysenteric patients. Materials and Methods This study is a randomized clinical trial, conducted on 100 children with dysentery who visited the outpatient Pediatric Clinic of Amirkabir Hospital in Arak, Iran. Patients were randomly divided into two equal intervention and control groups (n=50).The intervention group received antibiotics (ceftriaxone with a dose of 50mg/kg twice  per day [BID] until the symptoms of the patient improve and continue with oral Cefixime until the completion of the 5-day treatment period), and Golden Immunstim (two capsules per day for three days), and the control group only received routine antibiotics. The researchers assessed participants on days 3, 7 and 14. Data were analyzed using SPSS 23.0 software. Results On days 3, 7, and 14 abdominal cramp was in 12%, 2%, 0% in intervention group, respectively and was 16%, 0%, 0% in control group (p> 0.05); Diarrhea 8%, 2%, 0 % in intervention group, and 8%, 0%, 0%  in control group (p> 0.05). Vomiting was in 2%, 0%, 0% of intervention group and 0%, 0%, 0% of control group (p> 0.05); Fever was in 2%, 0%, 0% of intervention group and 6%, 0%, 0% of control group (p> 0.05). Conclusion According to the results of this study, it can be concluded that Golden Immunstim has no effect on dysentery symptoms.

Keywords:

Child, Diarrhea, Dysentery, Golden Immunstim

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COI code: JR_INJPM-6-5_012

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Ezati, Bahram; Mohammad Arjomandzadegan; Fatemeh Doreh & Ali Arjmand, 2018, Efficacy of Golden Immunstim for Improvement of Abdominal Cramp, Diarrhea, Vomiting, and Fever in Dysenteric Patients: A Randomized Clinical Trial, International Journal of Pediatrics 6 (5), https://www.civilica.com/Paper-JR_INJPM-JR_INJPM-6-5_012.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Ezati, Bahram; Mohammad Arjomandzadegan; Fatemeh Doreh & Ali Arjmand, 2018)
Second and more: (Ezati; Arjomandzadegan; Doreh & Arjmand, 2018)
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Type: Medical University
Paper No.: 412
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