Nanoparticles in Vaccine Development

Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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JR_JABR-1-4_001

تاریخ نمایه سازی: 29 آذر 1395

Abstract:

Vaccination has greatly improved human health. Despite of all improvements in this field, there is not an efficient vaccine for many diseases, and of the available ones, some could not produce a long-term immunity. Recently, there have been many researches on the applicability of nanostructures as an efficient system forvaccine delivery, and the initial results have been promising. Their potential adjuvanticity, capability of the stimulation of both humoral and cellular immunityresponses, more stability in environmental conditions, possible targeted vaccine delivery, the need for low quantity of proteins (in the case of subunit vaccines), etc., are of the main reasons that this area has gained many interests. Here, we try to review the main nanostructures that could be act as a delivery vehicle in vaccine delivery

Authors

Abbas Hajizade

Applied Biotechnology Research Centre,Baqiyatallah University of Medical Sciences, Tehran, Iran

Firouz Ebrahimi

Department of Biology, Faculty of Basic Sciences, Imam Hossein University, Tehran, Iran

Ali-Hatef Salmanian

Department of Plant biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

Ayyoob Arpanaei

Department of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran