Nanoparticles in Vaccine Development
Publish place: Journal of Applied Biotechnology Reports، Vol: 1، Issue: 4
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JABR-1-4_001
تاریخ نمایه سازی: 29 آذر 1395
Abstract:
Vaccination has greatly improved human health. Despite of all improvements in this field, there is not an efficient vaccine for many diseases, and of the available ones, some could not produce a long-term immunity. Recently, there have been many researches on the applicability of nanostructures as an efficient system forvaccine delivery, and the initial results have been promising. Their potential adjuvanticity, capability of the stimulation of both humoral and cellular immunityresponses, more stability in environmental conditions, possible targeted vaccine delivery, the need for low quantity of proteins (in the case of subunit vaccines), etc., are of the main reasons that this area has gained many interests. Here, we try to review the main nanostructures that could be act as a delivery vehicle in vaccine delivery
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Authors
Abbas Hajizade
Applied Biotechnology Research Centre,Baqiyatallah University of Medical Sciences, Tehran, Iran
Firouz Ebrahimi
Department of Biology, Faculty of Basic Sciences, Imam Hossein University, Tehran, Iran
Ali-Hatef Salmanian
Department of Plant biotechnology, National Institute for Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
Ayyoob Arpanaei
Department of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran