Biosynthesis of Srco3 nanostructures with honey as a green capping agent and reductant: photodynamic therapy

Objective (s): SrCO3 nanoparticles could be used as new biomedical sources in magnetic resonance imaging as a promising noninvasive imaging modality for the preoperative staging of breast cancer and monitoring of tumor response to therapy. The present study aimed to synthesize SrCO3 nanostructures using microwave irradiation in the presence of honey as a green capping agent and reductant. Materials and Methods: The optical properties of SrCO3 nanostructures were investigated using ultraviolet-visible (UV-Vis) spectroscopy. Sr(NO3)2.6H2O and NaOH were applied as the starting reagents. Fructose (32.56-38.2%) and glucose (28.54-31.3%), which were the main carbohydrates found in honey, were not only involved in stabilization, but they also acted as the reducing agents in the production of SrCO3 nanostructures. The produced nanostructures were characterized using X-ray diffraction analysis, Fourier transform infrared spectroscopy, scanning electron microscopy, and transmission electron microscopy.Results: Method of synthesis and chemical reagents were observed to affect the structural parameters, crystallite size, product size, morphology, and antioxidant activity. Conclusion: According to the results, honey could be used as a green capping agent and reductant for the synthesis of SrCO3 nanostructures as a novel structure to co-deliver therapeutic agents using photo-thermal agents. Moreover, honey has significant potential for diagnostic and therapeutic purposes in the future.

Keywords:

Capping Agent , Drug carriers , Photodynamic Therapy , SrCO3 NPs