Autoimmune Progesterone Dermatitis With Angioedema Caused by Exogenous Progesterone in a Pregnant Woman: A Case Report
Publish place: Razavi International Journal of Medicine، Vol: 3، Issue: 3
Publish Year: 1394
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_RIJO-3-3_006
تاریخ نمایه سازی: 6 اسفند 1398
Abstract:
Introduction: Autoimmune progesterone dermatitis (APD) is an uncommon immunologic condition accompanied with dermatologic manifestations and caused by an immune response to endogenous or exogenous progesterone in women during their reproductive years. We report a case of APD in a pregnant woman who received exogenous progesterone to prevent preterm delivery.Case Presentation: A 28-year-old female who was 17 weeks pregnant was referred to the emergency department with the complaint of progressive edema in the dorsal side of her right hand and progressive dyspnea. Intradermal skin test using 50 mg/mL progesterone resulted in 15 mm wheal in the injected area and approved the diagnosis of APD.Conclusions: Patients with APD may have very different symptoms requiring immediate care; therefore, being informed about this condition is necessary for the physicians in emergency and obstetrics and gynecology departments. Also a positive history of such condition in a pregnant woman necessitates precautions in the management of her pregnancy due to the potential of anaphylactic events.
Authors
Mohsen Salari Rad
Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Ehsan Bolvardi
Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Sima Salari Rad
Department of Psychiatry, Tabriz University of Medical Sciences, Tabriz, IR Iran- Honorary Fellow Research, Aberdeen Biomedical Imaging Centre, Aberdeen University, Aberdeen, UK