Antimicrobial resistance of bacterial isolates from bloodstream infections in a tertiary hospital, Tabriz

Background: Bloodstream infection is a serious condition associated with significant morbidity and mortality. Antimicrobial susceptibility patterns should guide the choice of empiric antimicrobial regimens for patients with bacteremia. Methods: The aim of this study was to assess pattern of antibiotic resistance in these bacteria isolated from an Educational-Health Care Center through 2015 to 2016. Antimicrobial drug susceptibility test was performed using the disc agar diffusion method according to CLSI recommendations. Results: In this study, among bacteria isolated from blood cultures most strains were Staphylococcus aureus (20.6%) and E. coli (20.6%) and the lowest isolated was Enterobacter spp. The most antibiotic sensitivity among all the bacteria isolated was belonged to amikacin and imipenem which was 43 (63.2%) and 41 (60.3%) respectively and the highest resistance among all bacteria isolated was related to co-trimoxazole and ceftriaxone which was 44 (64.7%) and 42 (61.8%) respectively. Conclusion: The results of this study shows resistance among bacteria isolated from blood cultures in the hospital setting and their developed resistance towards many conventional antibiotics, which is a concern at this treatment center.

Keywords:

Bloodstream infection , Antimicrobial resistance , Bacteria