A STUDY OF PREVALENCE OF SHIGELLA SPECIES AND ESBL PRODUCING ISOLATES IN ARDABIL, IRAN
Publish place: 19th International Congress of Microbiology of Iran
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
MEDISM19_245
تاریخ نمایه سازی: 13 مهر 1397
Abstract:
Background and Aim:Shigellosis is the main cause of gastrointestinal disease and is a public health concern worldwide. Nearly forty serotypes are clustered into 4 species includes: Shigella flexneri (S.flexneri), S. sonnei, S. boydii and S. dysenteriae that can cause insignificant to severe dysentery. The aim of this study was to determine the prevalence of S. sonnei and extended-spectrum beta-lactamases (ESBLs) isolates in Ardabil province.Methods:In this study, 1280 fecal samples were collected from patients and biochemical and molecular test (invc and wbyz genes for Shigella spp and shigella sonnei detection, respectively) were used to determine bacterial strains. In addition, Phenotyping of ESBL-producing Shigella isolates was performed using cefotaxime combined with ceftazidime in the presence or absence of clavulanic acid, as recommended by CLSI.Results:In total, biochemical tests revealed that 113 fecal samples were positive for shigella spp. Moreover, result of molecular tests revealed that 36 and 21 fecal samples were positive for shigella spp and Shigella sonnei, respectively. In the other hand, ESBLs were produced by 8 of the 36 (22.2 %) Shigella isolatesConclusion:The results suggested that there was a high prevalence of the shigella spp and shigella sonnei among patients with gastrointestinal disease, therefore, appropriate programs should be considered in order to control and treat the patients
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Authors
Sahar Sabouri
School of Medicine. Ardebil University of medical science. Ardebil.IR Iran
Taher Azimi
Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Hadi Peeri Dogaheh
School of Medicine. Ardebil University of medical science. Ardebil.IR Iran