ETHANOL EXTRACT MECHANISM OF RUMEX ALVEOLATUS ON CANDIDA ALBICANS

Background and Aim:Candida albicans is an opportunistic pathogenic yeast that is a common member of the human gut flora. Rumex alveolatus is traditionally used for the treatment of pain and inflammation The aim of this research was the study of the ethanol extract mechanism of R. alveolatus on Candida albicans.Methods:In the present study, the mechanism of anticandidial activity of R. alveolatus toward Amphotricin B was investigated by flame-photometry, outoanalyzer and HPLC.Results: Our results showed significant anticandidia effect of R. alveolatus. Ethanolic extract of R. alveolatus causes release of Na^+,K^+, glucose and aminoacids from candida albicans similar to Amphotricin B.Conclusion:Our study encourage examination of the efficacy of R. alveollatus against candida spp.

Keywords:

Rumex alveolatus , Candida albicans , HPLC , flame-photometry , outoanalyzer