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Authors COMPARATIVE EFFECT OF BIOACTIVE PEPTIDES ON TESTIS HISTOLOGICAL VARIATION BELOW HEAT STRESS IN MALE RATSMahsa Valizadeh - biology, urmia , iran
Vahid Nejati - biology, urmia , iran
Ali Shalizar Jalali - faculty of veterinary, urmia, iran
Ebrahim Hossein Najdegerami - biology, urmia , iran
Gholamreza Najafi Tazekand Ghaterrchi - faculty of veterinary, urmia, iran
Abstract:Background and Aim : Scrotal hyperthermia has been known as a cause of male infertility. Testicular heat stress even for a single short period can induce destruction in testicular tissue and spermatogenesis disturbances. Antioxidants play a basic role in both food systems and the human body, reducing oxidative activities. Peptides are biological molecules with small chains of amino acids that have high anti-inflammatory and antioxidant properties. In particular, fish protein hydrolysates (FPH) with antioxidant properties have become a topic of great interest for pharmaceutical and health foods.Methods : In present study, 35 adult male Wistar rats were randomly categorized into 5 groups; group 1 served as a control, groups 2 was heat-stressed (43 ◦C for 20 min per day). group 3,4 and 5 were heat-stressed along with Bioactive Peptides (5,10 and 20 mg kg-1 day, Oral Gavage, respectively). The HS was induced through immersion of experimental rat scrotums in a water bath. After 35 days, the testicles were harvested, then dehydrated, cleaned in xylene and embedded in paraffin wax. Thin sections were cut and stained with hematoxylin and eosin for histopathological analysis in all experimental groups.Results : In HS-exposed group, histological Alterations of Seminiferous tubules showed significant decrease in a temperature-dependent manner compared to the control group. There was no change in group 3 and 4 duos to severe tissue damage, but in group 5, Bioactive Peptides have positive effects on histological factors.Conclusion : In HS-exposed group, histological Alterations of Seminiferous tubules showed significant decrease in a temperature-dependent manner compared to the control group. There was no change in group 3 and 4 duos to severe tissue damage, but in group 5, Bioactive Peptides have positive effects on histological factors.
Keywords:Heat stress, BioactivePeptides, Seminiferous tubules, Rat
COI code: MHMIMED04_035
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Valizadeh, Mahsa; Vahid Nejati; Ali Shalizar Jalali; Ebrahim Hossein Najdegerami & Gholamreza Najafi Tazekand Ghaterrchi, 2019, COMPARATIVE EFFECT OF BIOACTIVE PEPTIDES ON TESTIS HISTOLOGICAL VARIATION BELOW HEAT STRESS IN MALE RATS, The Fourth Congress of Men, تهران, دانشگاه علوم پزشكي شهيد بهشتي, https://www.civilica.com/Paper-MHMIMED04-MHMIMED04_035.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Valizadeh, Mahsa; Vahid Nejati; Ali Shalizar Jalali; Ebrahim Hossein Najdegerami & Gholamreza Najafi Tazekand Ghaterrchi, 2019)
Second and more: (Valizadeh; Nejati; Shalizar Jalali; Hossein Najdegerami & Najafi Tazekand Ghaterrchi, 2019)
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