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title

Effect of Nandrolone Decanoate on Sertoli Cell and Testicular Tubular Differentiation Indices in Rats

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Year: 2019
COI code: RROYAN20_301
Paper Language: English

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Authors Effect of Nandrolone Decanoate on Sertoli Cell and Testicular Tubular Differentiation Indices in Rats

  P Farzipoour - Department of Biology, Urmia University, Urmia, Iran
  V Nejati - Department of Biology, Urmia University, Urmia, Iran
  E Hosein Najd Gerami - Department of Biology, Urmia University, Urmia, Iran
  A Shalizar-Jalali - Department of Basic Sciences, Urmia University, Urmia, Iran

Abstract:

Background: Misuse of Nandrolone Decanoate, an anabolic steroid, can lead to serious side effects including male infertil-ity.Materials and Methods: Eighteen rats were randomly assigned into 3 groups; group 1 was served as a control and groups 2 and 3 received 3 and 6 mg/kg of Nandrolone Decanoate weekly through intra-muscular injections, respectively. After 8 weeks, the testicles were harvested and Sertoli cell index (SCI) and tubular differentiation index (TDI) were evaluated.Results: The SCI and TDI indices showed significant reduc-tions in Nandrolone Decanoate-treated groups compared to the control group.Conclusion: The use of anabolic steroids such as Nandrolone Decanoate may cause testicular dysfunction.

Keywords:

Nandrolone Decanoate, Seminiferous Tubulest, Ser-toli Cell, Spermatogenesis, Rat

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COI code: RROYAN20_301

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Farzipoour, P; V Nejati; E Hosein Najd Gerami & A Shalizar-Jalali, 2019, Effect of Nandrolone Decanoate on Sertoli Cell and Testicular Tubular Differentiation Indices in Rats, 20th congress on reproductive biomedicine and 15th congress on stem cell biology & technology, تهران, پژوهشگاه رويان, https://www.civilica.com/Paper-RROYAN20-RROYAN20_301.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Farzipoour, P; V Nejati; E Hosein Najd Gerami & A Shalizar-Jalali, 2019)
Second and more: (Farzipoour; Nejati; Hosein Najd Gerami & Shalizar-Jalali, 2019)
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Type: state university
Paper No.: 11535
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