Branched Chain Amino Acids supplementation can reduce muscle injury and hasten recovery post-exercise: A systematic review and meta-analysis

Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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SRMMED22_026

تاریخ نمایه سازی: 19 آبان 1398

Abstract:

Objective: This systematic review and meta-analysis of present documents was conducted to obtain a definitive result for the BCAA administration on the DOMS and muscle damage indices after exercise. Design: Systematic review and meta-analysis. Data Sources: This literature search was conducted across the databases PubMed, Scopus, ISI Web of Science, SID (Scientific Information Database) and Cochrane Central Register of Controlled Trials and Cochrane Library database covering a period up to January 2017. Eligibility Criteria for Selecting Studies: Clinical trials evaluating BCAA administration subsequences on athletes were considered as being eligible. Results: A total of 42 studies were evaluated for eligibility, and 25 studies were excluded for the meta-analysis. According to the meta-analysis, BCAA supplementation significantly reduced CK levels 24 hours post-exercise (mean difference=-129.55 [95% CI: -237.02, -22.07] IU/l; P =0.018). Moreover, BCAA administration also significantly reduced in LDH immediately (mean difference=-10.11 [95% CI: -21.76, 1.53] IU/l; P =0.08) and 24 hours (mean difference=-14.66 [95% CI: -32.16, 2.83] IU/l; P =0.10) post-exercise. This article results suggested that BCAA consumption is inversely associated with DOMS at 24 (SMD=-0.43 [95% CI: -0.71, -0.16], p = 0.002), 48 (SMD=-0.55 [95% CI: -0.81, -0.29], p < 0.0001), and 72 (SMD=-0.44 [95% CI: -0.72, -0.16], p = 0.002) hours post-exercise. Conclusion: This systematic review and meta-analysis demonstrates that supplementation with BCAA can alleviate muscle damage in the first 24 h after the exercise and it seems that in the daily dose consumption, BCAA is more effective in athlete’s recovery rather than periodic doses.

Authors

Amirhossoein Ramezani Ahmadi

Nutrition and Metabolic Diseases Research Center, Ahvaz Junishapur University of Medical Sciences, Ahvaz, Iran

Elahe Palimi

Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Bahman Moradipoodeh

Nutrition and Metabolic Diseases Research Center, Ahvaz Junishapur University of Medical Sciences, Ahvaz, Iran

Mina Mahdipour

Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran