EVALUATION OF MECHANICAL AND ANTIBACTERIAL PROPERTIES OF WOUND DRESSING BASED ON CHITOSAN AND PLATANUS ORINTALIS LEAVES

During the process of wound healing, wound dressings are used for dermal and Epidermal repairing. This dressings as a permeable physical barrier to oxygen and moisture protect the wound against the penetration of icroorganisms.Natural biopolymers are widely used in restorative medicine due to the biofeatures such as bicompatibility, Biodegradability and the similarity to the extracellular matrix. Biopolymers such as polysaccharides are widely used in the development of wound dressings, because of the abundance in plants and products of the body. However films that are made from them have poor mechanical strenght. In this study Chitosan films incorporated with extract and powdered of platanus orientalis leaves prepared by casting method. Mechanical properties and water absorbtion capacity of the films were determind. .Highest water absorbtion capacity and elongation at break were obtained from powder-chitosan (P-C) film. The antimicrobial test was carried by agar diffusion and growth inhibition effects of the films including extract and powdered leaves were tested on gram positive microorganisms of staphylococcus aureus and enterococcus feacalis and gram negative microorganisms of Escherichia coli and pseudomonas aeruginosa. The extract-powder-chitosan( E-P-C) film showed the antimicrobial activity on all of microorganisms used in the study.

Keywords:

Chitosan , Antibacterial , Escherichia Coli , Pseudomonas , Staphylococcus