Evaluation of bedsore wounds in children and prevention of hospitalization infection using Arabic gum

Abstract: The subcutaneous or hypodermic tissue is the innermost layer of the skin, which is essentially of adipose tissue. The dermal attachment to the epidermis is a basal layer composed of collagen. This basal layer performs four different functions and acts as a scaffold for soft tissue organization. It is cite for regeneration that has selective permeability for serum filtration. Also, it is a barrier between different cell types, and cite where the epithelium subcutaneous to the cells. Untreated, bed sores can lead to serious complications, one of which is cellulite, a potentially life-threatening bacterial infection. As the bed sore wound spreads to the joints and bones, it may cause bone and joint infections that can damage the cartilage, tissue and reduce joint function. The bacteria can then enter the bloodstream through wounds, leading to shock and life-threatening conditions. Stage II wounds can heal in one to six weeks, but wounds that lead to stage three or four may last several months or may never heal, especially in children with health problems. The purpose of this study was to design bio-based wounds with gelatin, Gum Arabic, and polyurethane. The wounds were made with different bio composite specimens. The procedure is gelatin and gum Arabic were combined with certain percentages. The temperature of mixing and solubilization was set at 50°C. After complete fabrication of the material and complete dissolution of the samples in the solvent without any agglomeration, the samples were placed in a low-temperature freezer at -70°C and were placed in a freeze dryer. After the drying process is completed and the pores are ready on the wound heal sample, in the next stages several tests are carried out to check the suitability of the produced wounds. The SEM analysis was performed on bio-based wounds in which the results showed the suitability and porosity of these wound dress were suitable. The presence of proper porosity and moisture level for wound healing and non-acidity as well as the use of bed wound healing have been distinguished from other conventional wound healing product in the market and research domain.

Keywords:

Wound , Bed sore , Hospital infectious , Freeze drying , Soft tissue engineering