Cloning, expression, purification and antigenic evalution of vacA antigenic fragments recombinant protein of Helicobacter pylori
عنوان مقاله: Cloning, expression, purification and antigenic evalution of vacA antigenic fragments recombinant protein of Helicobacter pylori
شناسه ملی مقاله: CIGS12_0050
منتشر شده در دوازدهمین کنگره ژنتیک ایران در سال 1391
شناسه ملی مقاله: CIGS12_0050
منتشر شده در دوازدهمین کنگره ژنتیک ایران در سال 1391
مشخصات نویسندگان مقاله:
Leila Hasanzadeh - Department of Biotechnology and Microbiology, Arak University of Medical Sciences, Arak, Iran
Hamid Abtahi - Molecular and Medicine Research Center, Department of Microbiology, Arak University of Medical Sciences, Arak, Iran
Safieh Soufian - Department of Biology, Payame Noor University, Arak, Iran
Ehsanollah Ghaznavi-Rad - Department of Microbiology and immunology, Arak University of Medical Sciences, Arak, Iran
خلاصه مقاله:
Leila Hasanzadeh - Department of Biotechnology and Microbiology, Arak University of Medical Sciences, Arak, Iran
Hamid Abtahi - Molecular and Medicine Research Center, Department of Microbiology, Arak University of Medical Sciences, Arak, Iran
Safieh Soufian - Department of Biology, Payame Noor University, Arak, Iran
Ehsanollah Ghaznavi-Rad - Department of Microbiology and immunology, Arak University of Medical Sciences, Arak, Iran
Helicobacter pylori is one of the important pathogens that infected epithelial cells of stomach. The vacuolating cytotoxin (vacA) is major bacterial factor involved in gastric injury. The aim of this study was to construct a recombinant protein containing antigenic regions of vacA and determining its antigenicity as a vaccine candidate.
کلمات کلیدی: Helicobacter pylori, vacA cytotoxin, Cloning, antigeric regions
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/226323/